Article
Syndecan-2 expression in colorectal cancer-derived HT-29 M6 epithelial cells induces a migratory phenotype.
Biochemical and biophysical research communications - 31 Aug 2001
Contreras H R, Fabre M, Granés F, Casaroli-Marano R, Rocamora N, Herreros A G, Reina M, Vilaró S
Abstract excerpt
Members of the heparan sulfate proteoglycan family, the syndecans have emerged as integrators of extracellular signals, such as ECM components or growth factors, that activate cytoplasmic signaling cascades and regulate cytoskeletal functions. Specifically, syndecan-2 has been implicated in various cellular processes, from differentiation to migration, including its participation in cell-cell and cell-matrix...
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