Article
Mechanisms of glucose transport at the blood-brain barrier: an in vitro study.
Brain research - 15 Jun 2001
McAllister M S, Krizanac-Bengez L, Macchia F, Naftalin R J, Pedley K C, Mayberg M R, Marroni M, Leaman S, Stanness K A, Janigro D
Abstract excerpt
How the brain meets its continuous high metabolic demand in light of varying plasma glucose levels and a functional blood-brain barrier (BBB) is poorly understood. GLUT-1, found in high density at the BBB appears to maintain the continuous shuttling of glucose across the blood-brain barrier irrespective of the plasma concentration. We examined the process of glucose transport across a quasi-physiological in vitro...
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