Article
[Glucose metabolism in the basal ganglia].
Brain and nerve = Shinkei kenkyu no shinpo - 1 Apr 2009
Yamada Katsuya
Abstract excerpt
GABAergic neurons in the substantia nigra pars reticulata (SNr) -a major output nucleus of the basal ganglia- are involved in sensing severe hypoglycemic and hypoxic conditions in the brain via the ATP-sensitive potassium (KATP) channels that are abundantly expressed in these neurons. However, these neurons are also sensitive to mild changes in extracellular glucose concentrations through KATP...
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