Article
Cyclooxygenase 1 is not essential for hypophagic responses to interleukin-1 and endotoxin in mice.
Pharmacology, biochemistry, and behavior - 1 Jan 2000
Swiergiel A H, Dunn A J
Abstract excerpt
Numerous studies have shown that the effects of interleukin-1 (IL-1) and endotoxin (LPS) on behavior are sensitive to cyclooxygenase (COX) inhibitors. However, neither the location of the COX involved nor the specific isoform, COX1 or COX2, is known. A previous study using selective COX1 and COX2 inhibitors did not provide an unequivocal answer. Therefore, we tested the response of sweetened milk ingestion to...
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