Article
Epithelial growth fraction and expression of p53 tumour suppressor gene in oral submucous fibrosis.
Australian dental journal - 1 Apr 1996
Cox S C, Walker D M
Abstract excerpt
The incidence of squamous cell carcinoma in patients with oral submucous fibrosis (OSF) exceeds 7 per cent. The proliferative cell nuclear antigen (PCNA) is a convenient marker of epithelial cell proliferation and p53 tumour suppressor gene mutations or deletions are frequent in oral cancer. The present study estimated the basal epithelial cell growth fraction using a standard immunohistological method for the...
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