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Article

Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2.

Proceedings of the National Academy of Sciences of the United States of America - 18 Dec 2012

Luo Qianyi, Viste Kristin, Urday-Zaa Janny Concha, Senthil Kumar Ganesan, Tsai Wen-Wei, Talai Afsaneh, Mayo Kelly E, Montminy Marc, Radhakrishnan Ishwar

Abstract excerpt

Basic leucine zipper (bZip) transcription factors regulate cellular gene expression in response to a variety of extracellular signals and nutrient cues. Although the bZip domain is widely known to play significant roles in DNA binding and dimerization, recent studies point to an additional role for this motif in the recruitment of the transcriptional apparatus. For example, the cAMP response element binding...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23213254
DOI: 10.1073/pnas.1219028109
PMCID: PMC3529076

Genes

CRTC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2.PMID 23213254Read ↗

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