Article
ATRA(ouble) in the treatment of acute promyelocytic leukemia.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
Ozpolat B, Lopez-Berestein G, Mehta K
Abstract excerpt
Acute promyelocytic leukemia (APL) is a unique disease that responds to differentiation-inducing effects of all-trans-retinoic acid (ATRA). ATRA induces complete clinical remissions (CRs) in most patients and now constitutes a standard therapy in patients with APL. However, CRs induced by ATRA ar...
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