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Article

Characterization of the Human ABCG1 Gene

1 Oct 2001

Abstract excerpt

The human ABCG1 gene encodes a member of the ATP-binding cassette (ABC) superfamily of transporter proteins and is highly induced when macrophages are incubated with oxysterols. Using mRNA from oxysterol-treated human THP-1 cells together with 5'-rapid amplification of cDNA ends and polymerase chain reaction, we identified a novel ABCG1 transcript that encodes a putative protein of 786 residues containing a new...

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PMID: 11500512
DOI: 10.1074/jbc.m105863200

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