Article
Polymorphism in exon 6 of the dopamine D(2) receptor gene (DRD2) is associated with elevated blood pressure and personality disorders in men.
Journal of human hypertension - 1 Aug 2001
Rosmond R, Rankinen T, Chagnon M, Pérusse L, Chagnon Y C, Bouchard C, Björntorp P
Abstract excerpt
A deficient dopamine D(2) receptor (DA2) formation or action may contribute to hypertension via an increase of catecholamine release. In addition, Axis II personality disorders that appears odd or eccentric (cluster A) is associated with a low density of DA2. This study sought to examine if a NcoI restriction fragment length polymorphism (C to T transition) in exon 6 of the dopamine D(2) receptor gene (DRD2) was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
