Article
Polymorphisms of DRD4 and DRD3 and risk of avoidant and obsessive personality traits and disorders.
Psychiatry research - 15 Jul 2003
Joyce Peter R, Rogers Geraldine R, Miller Allison L, Mulder Roger T, Luty Suzanne E, Kennedy Martin A
Abstract excerpt
We investigated whether polymorphisms of the dopamine D4 receptor (DRD4) and polymorphisms of the dopamine D3 receptor (DRD3) were associated with personality disorder symptomatology rather than with personality traits such as novelty seeking. DNA was obtained from 145 depressed patients in a clinical trial. These patients were assessed for the presence of personality disorder symptoms and disorders. The 2-repeat...
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