Article
Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype.
Neuropathology and applied neurobiology - 1 Jun 2001
Brat D J, Gearing M, Goldthwaite P T, Wainer B H, Burger P C
Abstract excerpt
Ganglion cell tumours, including gangliogliomas and gangliocytomas, are low grade neoplasms with a mature neuronal component. Ganglion cells within these lesions occasionally exhibit neurodegenerative changes including neurofibrillary tangles (NFT) similar to those in Alzheimer's disease. The frequency and spectrum of degenerative pathology in these lesions have not been defined, nor has their relation to patient...
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