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Article

A novel tau mutation, p.K317N, causes globular glial tauopathy.

Acta neuropathologica - 1 Aug 2015

Tacik Pawel, DeTure Michael, Lin Wen-Lang, Sanchez Contreras Monica, Wojtas Aleksandra, Hinkle Kelly M, Fujioka Shinsuke, Baker Matthew C, Walton Ronald L, Carlomagno Yari, Brown Patricia H, Strongosky Audrey J, Kouri Naomi, Murray Melissa E, Petrucelli Leonard, Josephs Keith A, Rademakers Rosa, Ross Owen A, Wszolek Zbigniew K, Dickson Dennis W

Abstract excerpt

Globular glial tauopathies (GGTs) are 4-repeat tauopathies neuropathologically characterized by tau-positive, globular glial inclusions, including both globular oligodendroglial inclusions and globular astrocytic inclusions. No mutations have been found in 25 of the 30 GGT cases reported in the l...

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Identifiers

PMID: 25900293
DOI: 10.1007/s00401-015-1425-0
PMCID: PMC5039015

Genes

MAPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25900293-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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