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Article

Neuropathology of Gerstmann-Sträussler-Scheinker disease.

Microscopy research and technique - 1 Jul 2000

Bugiani O, Giaccone G, Piccardo P, Morbin M, Tagliavini F, Ghetti B

Abstract excerpt

Gerstmann-Sträussler-Scheinker disease is a familial neurodegeneration characterized clinically by adult-onset ataxia, postural abnormalities, and cognitive decline, and pathologically by amyloid deposits mostly localized in the cerebral and cerebellar cortices and the basal ganglia. The disease is due to mutations in the prion protein gene. Processing of the mutant proteins originates the amyloidogenic fragments...

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Source

Identifiers

PMID: 10871543
DOI: 10.1002/1097-0029(20000701)50:1<10::AID-JEMT3>3.0.CO;2-6

Genes

GSS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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