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Article

Flexibility of TCR repertoire and permissiveness of HLA-DR3 molecules in experimental autoimmune thyroiditis in nonobese diabetic mice.

Journal of autoimmunity - 1 Aug 2001

Flynn J C, Fuller B E, Giraldo A A, Panos J C, David C S, Kong Y C

Abstract excerpt

Experimental autoimmune thyroiditis (EAT) is inducible in genetically susceptible mice by immunization with mouse thyroglobulin (mTg). With susceptibility linked to MHC class II, EAT is useful in studying human leukocyte antigen (HLA) associations with Hashimoto's thyroiditis. In non-obese diabetic (NOD) mice, approximately 10% thyroiditis incidence occurs with aging. This potential was exploited to examine the T...

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Share to HLA-DR3 Antigen
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Receptors, Antigen, T-Cell, alpha-beta

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Source

Identifiers

PMID: 11488633
DOI: 10.1006/jaut.2001.0528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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