Article
Characterization of mother-infant HIV type 1 gag p17 sequences associated with perinatal transmission.
AIDS research and human retroviruses - 1 Jul 1999
Hahn T, Matala E, Chappey C, Ahmad N
Abstract excerpt
The gag p17 matrix sequences of human immunodeficiency virus type 1 (HIV-1) from seven infected mother-infant pairs were analyzed after perinatal transmission. The p17 matrix open reading frame was maintained in 143 of the 166 clones analyzed (86.2% frequency of intact p17 open reading frames). The functional domains essential for p17 matrix function in HIV-1 replication, including targeting of Gag to the plasma...
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