Uncleaved NS2-3 Is Required for Production of Infectious Bovine Viral Diarrhea Virus

doi:10.1128/jvi.78.5.2414-2425.2004

Article

Uncleaved NS2-3 Is Required for Production of Infectious Bovine Viral Diarrhea Virus

13 Feb 2004

Abstract excerpt

Despite increasing characterization of pestivirus-encoded proteins, functions for nonstructural (NS) proteins NS2, NS2-3, NS4B, and NS5A have not yet been reported. Here we investigated the function of bovine viral diarrhea virus (BVDV) uncleaved NS2-3. To test whether NS2-3 has a discrete function, the uncleaved protein was specifically abolished in two ways: first by inserting a ubiquitin monomer between NS2...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.