Article
cis-acting RNA elements required for replication of bovine viral diarrhea virus-hepatitis C virus 5' nontranslated region chimeras.
RNA (New York, N.Y.) - 1 Nov 1998
Frolov I, McBride M S, Rice C M
Abstract excerpt
Pestiviruses, such as bovine viral diarrhea virus (BVDV), share many similarities with hepatitis C virus (HCV) yet are more amenable to virologic and genetic analysis. For both BVDV and HCV, translation is initiated via an internal ribosome entry site (IRES). Besides IRES function, the viral 5' n...
Topics
- 5' Untranslated Regions
- Animals
- Base Sequence
- Cattle
- Cell Line
- Diarrhea Viruses, Bovine Viral
- Encephalomyocarditis virus
- Genome, Viral
- Hepacivirus
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Nucleic Acid Conformation
- Open Reading Frames
- Phenotype
- Protein Biosynthesis
- RNA, Viral
- Regulatory Sequences, Nucleic Acid
- Selection, Genetic