Article
Early development of the gubernaculum and cremaster sac in estrogen receptor knockout mice.
Urological research - 1 Jun 2001
Bartlett J E, Washburn T, Eddy E M, Korach K S, Temelcos C, Hutson J M
Abstract excerpt
AIM exogenous estrogen causes gubernacular atrophy and cryptorchidism in fetal rodents. Mice with an estrogen receptor-alpha (ERalpha) disrupted gene mutation (alphaERKO) were studied to determine whether ablation of endogenous estrogen action, through ERalpha, had an effect on gubernacular development. Serial sagittal sections were made of the pelvis in fetal and day 7 postnatal wild-type and alphaERKO mice with...
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