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Article

Characterization of the ovarian and reproductive abnormalities in prepubertal and adult estrogen non-responsive estrogen receptor alpha knock-in (ENERKI) mice.

Steroids - 1 Nov 2009

Sinkevicius K W, Woloszyn K, Laine M, Jackson K S, Greene G L, Woodruff T K, Burdette J E

Abstract excerpt

Estrogen non-responsive estrogen receptor alpha (ERalpha) knock-in (ENERKI) mice have a mutation (glycine 525 to leucine, G525L) in the ligand-binding domain of ERalpha. The mutant ERalpha protein has a significantly lower affinity and response to endogenous estrogens, while not altering growth f...

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Identifiers

PMID: 19631674
DOI: 10.1016/j.steroids.2009.06.012
PMCID: PMC2752961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19631674-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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