Article
Selection of HCV NS5A quasispecies during IFN therapy in patients with chronic HCV.
Digestive diseases and sciences - 1 Jul 2001
Paterson M, Laxton C, Goldin R D, Ackrill A M, Foster G R
Abstract excerpt
Interferon treatment of chronic hepatitis C virus infection is successful in a minority of patients. The sequence of the interferon sensitivity determining region (ISDR) of the NS5A protein may determine the outcome of therapy in patients infected with HCV genotype 1. To determine whether IFN tre...
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