Article
Evidence for the "midline" hypothesis in associated defects of laterality formation and multiple midline anomalies.
American journal of medical genetics - 15 Jul 2001
Gilbert-Barness E, Debich-Spicer D, Cohen M M, Opitz J M
Abstract excerpt
A male infant was liveborn at 38 weeks of gestation to a G4P1AB2, 22-year-old, mother. Polyhydramnios and multiple congenital anomalies were noted by ultrasonography; the infant died 5 min after birth. At autopsy, the infant had multiple defects of blastogenesis including midline anomalies with asplenia and abnormalities of laterality formation. The laterality defects were unusual in that they combined asplenia...
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