Article
Clinical analysis of families with heart, midline, and laterality defects.
American journal of medical genetics - 15 Jul 2001
Morelli S H, Young L, Reid B, Ruttenberg H, Bamshad M J
Abstract excerpt
Disturbances of the normal asymmetric placement of organs, such as polysplenia or situs inversus, have been defined traditionally as laterality defects. However, there is compelling evidence from vertebrate models and human birth defects to hypothesize that defects of the midline, isolated congenital heart defects, and laterality defects are etiologically related. We present the clinical characteristics of three...
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