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Article

Reverse transcriptase incorporation of 1,5-anhydrohexitol nucleotides.

Nucleic acids research - 1 Aug 2001

Vastmans K, Froeyen M, Kerremans L, Pochet S, Herdewijn P

Abstract excerpt

Several reverse transcriptases were studied for their ability to accept anhydrohexitol triphosphates, having a conformationally restricted six-membered ring, as substrate for template-directed synthesis of HNA. It was found that AMV, M-MLV, M-MLV (H(-)), RAV2 and HIV-1 reverse transcriptases were able to recognise the anhydrohexitol triphosphate as substrate and to efficiently catalyse the incorporation of one...

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Identifiers

PMID: 11470872
DOI: 10.1093/nar/29.15.3154
PMCID: PMC55830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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