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The importance of using absolute mutant frequencies to compare mutation spectra.

Mutation research - 8 Aug 2001

Kuipers G K, Slotman B J, Lafleur M V

Abstract excerpt

Because damage to the cellular DNA is very hazardous for a cell, it is important to identify compounds, which can cause DNA damage. To investigate the mutagenic effect of a particular agent of interest, usually mutation spectra are determined in a selected target gene. The most commonly used method to compare different mutation spectra with each other, is the comparison of the percentages of each type of...

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PMID: 11470484
DOI: 10.1016/s0027-5107(01)00155-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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