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Article

Down modulation of IL‐18 expression by human papillomavirus type 16 E6 oncogene via binding to IL‐18

17 Jul 2001

Abstract excerpt

To understand modulation of a novel immune-related cytokine, interleukin-18, by human papillomavirus type (HPV) 16 oncogenes, HaCaT, normal keratinocyte cell line, and C-33A, HPV-negative cervical cancer cell line, were prepared to establish stable cell lines expressing E6, E6 mutant (E6m), E6E7, or E7 constitutively. Expressions of various HPV oncogene transcripts were identified by RT-PCR. Expression of HPV...

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PMID: 11470273
DOI: 10.1016/s0014-5793(01)02652-7

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