Article
Two rare confounding polymorphisms proximal to the factor V Leiden mutation.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology - 1 Jun 2001
Gold B, Hanson M, Dean M
Abstract excerpt
BACKGROUND: Comprehensive assessment of thrombophilia risk includes characterization of the R506Q (Leiden) mutation in factor V in many patients. Although activated protein C resistance is often assessed by means of a coagulation test, molecular interrogation of the G1691A mutation provides confirmation and interpretive utility in patients undergoing anticoagulation. Many molecular methods are available to...
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