Article
Two novel fibrinogen variants found in patients with pulmonary embolism and their families.
Journal of thrombosis and haemostasis : JTH - 1 Jun 2003
Hanss M M L, Ffrench P O, Mornex J F, Chabuet M, Biot F, De Mazancourt P, Dechavanne M
Abstract excerpt
BACKGROUND: The occurrence of dysfibrinogen is quite rare in comparison with other hemostatic defects, specially in cases of venous thrombosis. OBJECTIVES: Fibrinogen is known to have multiple functions, which are not evaluated by simple coagulation testing. We have used gel electrophoresis to search for new mutations. PATIENTS AND METHODS: Specimens of purified fibrinogen from 217 consecutive patients with...
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