Article
The carboxin-binding site on Paracoccus denitrificans succinate:quinone reductase identified by mutations.
Journal of bioenergetics and biomembranes - 1 Apr 2001
Matsson M, Hederstedt L
Abstract excerpt
Succinate:quinone reductase catalyzes electron transfer from succinate to quinone in aerobic respiration. Carboxin is a specific inhibitor of this enzyme from several different organisms. We have isolated mutant strains of the bacterium Paracoccus denitrificans that are resistant to carboxin due to mutations in the succinate:quinone reductase. The mutations identify two amino acid residues, His228 in SdhB and...
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