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Article

Investigation of G2-phase chromosomal radiosensitivity in hereditary non-polyposis colorectal cancer cells.

International journal of radiation biology - 1 Jul 2001

Franchitto A, Pichierri P, Genuardi M, De Santis A, Palitti F

Abstract excerpt

PURPOSE: To investigate whether cells from hereditary nonpolyposis colorectal cancer (HNPCC) patients, a genetic condition characterized by constitutional mutations in DNA mismatch repair genes and associated with predisposition to colorectal carcinoma (CRC), could present a higher G2 chromosomal radiosensitivity. It is generally hypothesized that cancer predisposition in HNPCC is associated with the loss of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Source

Identifiers

PMID: 11454277
DOI: 10.1080/09553000110050056

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Investigation of G2-phase chromosomal radiosensitivity in hereditary non-polyposis colorectal cancer cells.PMID 11454277Read ↗

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Chromosomal sensitivity to X-ray irradiation during the G2 phase in lymphocytes of patients with hereditary cutaneous malignant melanoma as compared to healthy controls.Semantic proximity Read ↗

Mismatch Repair and the Hereditary Non-polyposis Colorectal Cancer Syndrome (HNPCC)Semantic proximity Read ↗

Molecular genetics of hereditary non-polyposis colorectal cancer (HNPCC).Semantic proximity Read ↗

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