Article
Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240-->Gly.
Antimicrobial agents and chemotherapy - 1 Aug 2001
Bonnet R, Dutour C, Sampaio J L, Chanal C, Sirot D, Labia R, De Champs C, Sirot J
Abstract excerpt
Three clinical strains (Escherichia coli Rio-6, E. coli Rio-7, and Enterobacter cloacae Rio-9) collected in 1996 and 1999 from hospitals in Rio de Janeiro (Brazil) were resistant to broad-spectrum cephalosporins and gave a positive double-disk synergy test. Two bla(CTX-M) genes encoding beta-lactamases of pl 7.9 and 8.2 were implicated in this resistance: the bla(CTX-M-9) gene observed in E. coli Rio-7 and E....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.