Article
PACSIN2 is a regulator of the metalloprotease/disintegrin ADAM13.
Developmental biology - 1 Nov 2000
Cousin H, Gaultier A, Bleux C, Darribère T, Alfandari D
Abstract excerpt
ADAM13 is a cell surface metalloprotease expressed in cephalic neural crest cells during early Xenopus development. The cytoplasmic domain of ADAM13 contains three potential SH3 (Src homology type 3) binding sites, suggesting that this region may support interactions with intracellular proteins. In this report we describe the identification, by a new strategy, of three proteins that bind the ADAM13 cytoplasmic...
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