Article
Tau gene mutations and neurodegeneration.
Biochemical Society symposium - 1 Jan 2001
Goedert M, Spillantini M G
Abstract excerpt
Abundant neurofibrillary lesions made of the microtubule-associated protein tau constitute a defining neuropathological characteristic of Alzheimer's disease. Filamentous tau protein deposits are also the defining neuropathological characteristic of other neurodegenerative diseases, many of which are frontotemporal dementias or movement disorders, such as Pick's disease, progressive supranuclear palsy and...
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