Article
Changing a single amino acid residue switches processive and non-processive behavior of Aspergillus niger endopolygalacturonase I and II.
The Journal of biological chemistry - 7 Sept 2001
Pages S, Kester H C, Visser J, Benen J A
Abstract excerpt
Processivity, also known as multiple attack on a single chain, is a feature commonly encountered only in enzymes in which the substrate binds in a tunnel. However, of the seven Aspergillus niger endopolygalacturonases, which have an open substrate binding cleft, four enzymes show processive behavior, whereas the other endopolygalacturonases are randomly acting enzymes. In a previous study (Benen, J.A.E., Kester,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.