Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No association between DLST gene and Alzheimer's disease or Wernicke-Korsakoff syndrome.

Neurobiology of aging - 1 Jan 2000

Matsushita S, Arai H, Yuzuriha T, Kato M, Matsui T, Urakami K, Higuchi S

Abstract excerpt

Among many candidate genes for the genetically heterogeneous Alzheimer's disease (AD), only apolipoprotein E (ApoE) has been confirmed. Another candidate is the dihydrolipoyl succinyltransferase (DLST) gene, one of three components of thiamine-dependent mitochondrial alpha-ketoglutarate dehydrogenase complex (KGDHC), because KGDHC activity is reported reduced in AD patients. Also characterized by reduced KGDHC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyltransferases
Share to Alcoholism
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Apolipoproteins E

Share to Cognition Disorders

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 11445257
DOI: 10.1016/s0197-4580(01)00225-1

Genes

DLST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

No association between DLST gene and Alzheimer's disease or Wernicke-Korsakoff syndrome.PMID 11445257Read ↗

Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population.Semantic proximity Read ↗

A DLST genotype associated with reduced risk for Alzheimer's disease.Semantic proximity Read ↗

Mutation analysis of the chromosome 14q24.3 dihydrolipoyl succinyltransferase (DLST) gene in patients with early-onset Alzheimer disease.Semantic proximity Read ↗

[Association between DLST gene polymorphism and Alzheimer's disease].Semantic proximity Read ↗

Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population.Semantic proximity Read ↗

Lack of association between TrkA single nucleotide polymorphisms and sporadic Alzheimer's disease in a Japanese population.Semantic proximity Read ↗

TAU haplotype and the Saitohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease.Semantic proximity Read ↗

No evidence for genetic association or linkage of the cathepsin D (CTSD) exon 2 polymorphism and Alzheimer disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.