Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulation of constitutive and heavy metal-induced metallothionein-I expression by nuclear factor I.

Gene expression - 1 Jan 2001

Majumder S, Ghoshal K, Gronostajski R M, Jacob S T

Abstract excerpt

Although the existence of repressor protein(s) involved in the regulation of highly inducible metallothionein-I (MT-I) gene expression has been postulated, none has been identified to date. We considered nuclear factor I (NFL) protein as a potential repressor, as three half-sites for NFI binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadmium
Share to CCAAT-Enhancer-Binding Proteins
Share to Electrophoretic Mobility Shift Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metallothionein

Share to Metals, Heavy

Share to NFI Transcription Factors

Share to Response Elements

Share to Y-Box-Binding Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 11444530
DOI: 10.3727/000000001783992588
PMCID: PMC5964943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11444530-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulation of constitutive and heavy metal-induced metallothionein-I expression by nuclear factor I.PMID 11444530Read ↗

Human Metallothionein Expression under Normal and Pathological Conditions: Mechanisms of Gene Regulation Based on In silico Promoter AnalysisSemantic proximity Read ↗

The zinc-sensing transcription factor MTF-1 mediates zinc-induced epigenetic changes in chromatin of the mouse metallothionein-I promoter.Semantic proximity Read ↗

The "metal transcription factor" MTF-1: biological facts and medical implicationsSemantic proximity Read ↗

Positive and negative regulators of the metallothionein gene (Review)Semantic proximity Read ↗

Putative zinc-sensing zinc fingers of metal-response element-binding transcription factor-1 stabilize a metal-dependent chromatin complex on the endogenous metallothionein-I promoter.Semantic proximity Read ↗

Transcriptional activity and regulatory protein binding of metal-responsive elements of the human metallothionein-IIA gene.Semantic proximity Read ↗

The DNA Binding Activity of Metal Response Element-binding Transcription Factor-1 Is Activated in vivo and in Vitro by Zinc, but Not by Other Transition MetalsSemantic proximity Read ↗

Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.Semantic proximity Read ↗

C-terminal deletion mutant of MRE-binding transcription factor-1 inhibits MRE-driven gene expression.Semantic proximity Read ↗

Functional analyses of the human metallothionein-IG gene. In vitro and in vivo studies.Semantic proximity Read ↗

An autoregulatory loop controlling CYP1A1 gene expression: role of H(2)O(2) and NFI.Semantic proximity Read ↗

Individual variability in the zinc inducibility of metallothionein-IIA mRNA in human lymphocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.