Article
Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population-based study.
Genetic epidemiology - 1 Jul 2001
Antoniou A C, Pharoah P D, McMullan G, Day N E, Ponder B A, Easton D
Abstract excerpt
We used data from a population based series of breast cancer patients to investigate the genetic models that can best explain familial breast cancer not due to the BRCA1 and BRCA2 genes. The data set consisted of 1,484 women diagnosed with breast cancer under age 55 registered in the East Anglia Cancer registry between 1991-1996. Blood samples taken from the patients were analysed for mutations in BRCA1 and...
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