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Article

Mutational analysis of <i>TSC1</i> and <i>TSC2</i> genes in gangliogliomas

1 Apr 2001

Abstract excerpt

Gangliogliomas constitute the most frequent tumour entity in patients with temporal lobe epilepsy. The characteristic histopathological admixture of glial and neuronal elements, the focal nature and their differentiated phenotype and benign biological behaviour suggest an origin from a developmentally compromised or dysplastic precursor lesion. The present study analysed TSC1 and TSC2 genes as potential...

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PMID: 11437991
DOI: 10.1046/j.0305-1846.2001.00302.x

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