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Article

Frequency of TSC1 and TSC2 mutations in American, British, Polish and Taiwanese populations.

Molecular medicine reports - 1 Sept 2013

Jóźwiak Jarosław, Sontowska Iwona, Płoski Rafał

Abstract excerpt

Tuberous sclerosis (TS) is caused by mutation of the tumor suppressor genes, tuberous sclerosis complex 1 (TSC1) or 2 (TSC2). The aim of the present study was to compare the frequency and types of TSC1 and TSC2 mutations in American, British, Polish and Taiwanese populations. A meta‑analysis of 380 TS patients was performed. Significant differences were analyzed using the Chi-square test and one-way ANOVA...

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Source

Identifiers

PMID: 23846400
DOI: 10.3892/mmr.2013.1583

Genes

TSC1
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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