Article
Analysis of a polymorphism in the tuberous sclerosis (TSC2) gene does not predispose to schizophrenia.
European archives of psychiatry and clinical neuroscience - 1 Jan 1998
Przkora R, Falkai P, von Deimling A, Wiestler O D, Albus M, Rietschel M, Maier W, Bayer T A
Abstract excerpt
The tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the development of malformations in various organs including the brain. A polymorphism in the TSC2 gene has been found to be increased in gangliogliomas, a lesion which is associated with disturbed neuro-glial cell migration pattern. Since these pathomorphological changes are compatible with disturbed neuronal migration in...
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