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Article

Paraoxonase 1 phenotype distribution and activity differs in subjects with newly diagnosed Type 2 diabetes (the CODAM Study).

Diabetic medicine : a journal of the British Diabetic Association - 1 Feb 2008

van den Berg S W, Jansen E H J, Kruijshoop M, Beekhof P K, Blaak E, van der Kallen C J, van Greevenbroek M M, Feskens E J M

Abstract excerpt

AIMS: Paraoxonase 1 (PON1) is an antioxidant high-density lipoprotein-bound enzyme, which was recently found to be expressed in the islets of Langerhans. A substitution (Q/R) at position 192 results in enzymes with different activity. Oxidation has been implicated in the onset of diabetes, and it can be hypothesized that PON1 may have a protective effect on diabetes. Our aim was to compare PON1 activities and...

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Share to Aryldialkylphosphatase
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diagnosis, Differential

Share to PON1 gene

Share to Glucose Intolerance

Share to Lipoproteins, LDL

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Source

Identifiers

PMID: 18290860
DOI: 10.1111/j.1464-5491.2007.02328.x

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Paraoxonase 1 phenotype distribution and activity differs in subjects with newly diagnosed Type 2 diabetes (the CODAM Study).PMID 18290860Read ↗

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