Article
Oxidative stress and renal dysfunction in salt-sensitive hypertension.
Kidney & blood pressure research - 1 Jan 2001
Trolliet M R, Rudd M A, Loscalzo J
Abstract excerpt
Hypertension is a risk factor for the development of end-stage renal disease. The mechanisms underlying hypertensive nephropathy are poorly understood. There is evidence, however, that in hypertension there is an accumulation of partially reduced oxygen and its derivatives, known collectively as reactive oxygen species, which may contribute to progressive renal dysfunction. In the present study, we assess the...
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