Article
The effects of flecainide on ATP-sensitive K(+) channels in pig urethral myocytes.
British journal of pharmacology - 1 Jul 2001
Yunoki T, Teramoto N, Naito S, Ito Y
Abstract excerpt
The effects of the antiarrhythmic drug flecainide on levcromakalim-induced hyperpolarization, macroscopic and unitary K(+) currents in pig urethra were investigated using patch-clamp techniques. The effects of flecainide were also examined on currents in inside-out patches of COS7 cells expressing carboxy terminus truncated inwardly rectifying K(+) channel (Kir6.2) subunits (i.e. Kir6.2DeltaC36) which form...
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