Article
The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions.
Journal of bacteriology - 1 Jul 2001
Hoa N T, Brannigan J A, Cutting S M
Abstract excerpt
During spore formation in Bacillus subtilis, the SpoIVB protein is a critical component of the sigma(K) regulatory checkpoint. SpoIVB has been shown to be a serine peptidase that is synthesized in the spore chamber and which self-cleaves, releasing active forms. These forms can signal proteolytic processing of the transcription factor sigma(K) in the outer mother cell chamber of the sporulating cell. This forms...
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