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Article

Induction and characterization of neutralizing antibodies against a human immunodeficiency virus type 1 primary isolate.

Journal of virology - 1 Jul 2001

Chen C H, Jin L, Zhu C, Holz-Smith S, Matthews T J

Abstract excerpt

Chimpanzees infected with the primary isolate DH012 mount potent neutralizing antibodies. This DH012 neutralizing activity is highly strain specific. Immune sera from guinea pigs immunized with recombinant DH012 gp120 could also neutralize this primary isolate. The neutralizing activity in chimpanzee and guinea pig sera against wild-type DH012 appears to be independent of a linear epitope in the V3 region of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11413338
DOI: 10.1128/JVI.75.14.6700-6704.2001
PMCID: PMC114394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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