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Article

Prime-boost immunization of rabbits with HIV-1 gp120 elicits potent neutralization activity against a primary viral isolate.

PloS one - 1 Jan 2013

Narayan Kristin M, Agrawal Nitish, Du Sean X, Muranaka Janelle E, Bauer Katherine, Leaman Daniel P, Phung Pham, Limoli Kay, Chen Helen, Boenig Rebecca I, Wrin Terri, Zwick Michael B, Whalen Robert G

Abstract excerpt

Development of a vaccine for HIV-1 requires a detailed understanding of the neutralizing antibody responses that can be experimentally elicited to difficult-to-neutralize primary isolates. Rabbits were immunized with the gp120 subunit of HIV-1 JR-CSF envelope (Env) using a DNA-prime protein-boost...

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Share to AIDS Vaccines
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23326351
DOI: 10.1371/journal.pone.0052732
PMCID: PMC3541383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23326351-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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