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Article

Variation at Interleukin-10 Locus Represents Susceptibility to Psoriasis in North Indian Population.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2019

Aadil Wani, Kaur Rajinder, Ganai Bashir Ahmad, Akhtar Tahseena, Narang Tarun, Hassan Iffat, Kumar Sunil

Abstract excerpt

BACKGROUND: IL-10 is an important pleiotropic, immunoregulatory and anti-inflammatory cytokine which plays a significant role in the pathogenesis of psoriasis. OBJECTIVE: The aim of the present study was to determine whether the three polymorphic sites of the IL-10 gene, haplotype and serum level confer susceptibility to psoriasis. METHOD: 200 psoriatic patients and 200 controls were genotyped for three IL-10...

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PMID: 30147018
DOI: 10.2174/1871530318666180821161629

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