Article
Interleukin-10 promoter polymorphism IL10.G and familial early onset psoriasis.
The British journal of dermatology - 1 Aug 2003
Hensen P, Asadullah K, Windemuth C, Rüschendorf F, Hüffmeier U, Ständer M, Schmitt-Egenolf M, Wienker T F, Reis A, Traupe H
Abstract excerpt
BACKGROUND: The anti-inflammatory cytokine interleukin (IL)-10 is considered to play a major role in the pathophysiology of psoriasis, which is characterized by an IL-10 deficiency. Systemic administration of IL-10 has been shown to be an effective therapy for psoriasis. The IL-10 promoter region...
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