Article
PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus.
Biochemical and biophysical research communications - 30 Mar 2001
Iwamura T, Yoneyama M, Koizumi N, Okabe Y, Namiki H, Samuel C E, Fujita T
Abstract excerpt
Virus infection triggers innate responses to host cells including production of type I interferon (IFN). Since IFN production is also induced by treatment with poly(I:C), viral double-stranded (ds) RNA has been postulated to play a direct role in the process. In the present study, we investigated...
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