Article
Fluorescent in situ hybridization and ex vivo 1H magnetic resonance spectroscopic examinations of meningioma tumor tissue: is it possible to identify a clinically-aggressive subset of benign meningiomas?
Neurosurgery - 1 Nov 2007
Pfisterer Wolfgang K, Hendricks William P, Scheck Adrienne C, Nieman Ronald A, Birkner Thomas H, Krampla Wolfgang W, Preul Mark C
Abstract excerpt
OBJECTIVE: Although histologically benign, Grade I meningiomas can sometimes behave aggressively. The clinically-aggressive subset of Grade I meningiomas is typically indistinguishable from clinically-benign Grade I meningiomas in vivo. We compared molecular genetic and biochemical findings to clinical, pathological, and immunohistochemical information in a series of clinically-aggressive Grade I meningiomas with...
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