Global versus local regulatory roles for Lrp-related proteins: Haemophilus influenzae as a case study.

doi:10.1128/JB.183.13.4004-4011.2001

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Global versus local regulatory roles for Lrp-related proteins: Haemophilus influenzae as a case study.

Journal of bacteriology - 1 Jul 2001

Friedberg D, Midkiff M, Calvo J M

Abstract excerpt

Lrp (leucine-responsive regulatory protein) plays a global regulatory role in Escherichia coli, affecting expression of dozens of operons. Numerous lrp-related genes have been identified in different bacteria and archaea, including asnC, an E. coli gene that was the first reported member of this family. Pairwise comparisons of amino acid sequences of the corresponding proteins shows an average sequence identity...

Topics

Acetolactate Synthase
Amino Acid Sequence
Bacterial Proteins
DNA-Binding Proteins
Escherichia coli Proteins
Gene Expression Profiling
Gene Expression Regulation, Bacterial
Genes, Bacterial
Haemophilus influenzae
Leucine-Responsive Regulatory Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Phenotype

Protein Binding

Sequence Homology, Amino Acid

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 11395465
DOI: 10.1128/JB.183.13.4004-4011.2001
PMCID: PMC95284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global versus local regulatory roles for Lrp-related proteins: Haemophilus influenzae as a case study.PMID 11395465Read ↗

Leucine-responsive regulatory protein: a global regulator of gene expression in E. coli.Semantic proximity Read ↗

Limited functional conservation of a global regulator among related bacterial genera: Lrp in Escherichia, Proteus and Vibrio.Semantic proximity Read ↗

Regulation of the Escherichia coli lrp gene.Semantic proximity Read ↗

Lack of expression of the global regulator OxyR in Haemophilus influenzae has a profound effect on growth phenotype.Semantic proximity Read ↗

The lrp gene and its role in type I fimbriation in Citrobacter rodentium.Semantic proximity Read ↗

Two operons that encode FNR-like proteins in Lactococcus lactis.Semantic proximity Read ↗

Leucine-responsive regulatory protein (Lrp) acts as a virulence repressor in Salmonella enterica serovar Typhimurium.Semantic proximity Read ↗

Variation in expression of the Haemophilus influenzae HMW adhesins: a prokaryotic system reminiscent of eukaryotes.Semantic proximity Read ↗

Haemophilus influenzae Protein F Mediates Binding to Laminin and Human Pulmonary Epithelial CellsSemantic proximity Read ↗

The global regulator Lrp contributes to mutualism, pathogenesis and phenotypic variation in the bacterium Xenorhabdus nematophila.Semantic proximity Read ↗

Escherichia coli leucine-responsive regulatory protein (Lrp) controls lysyl-tRNA synthetase expression.Semantic proximity Read ↗

Escherichia coli Lrp (leucine-responsive regulatory protein) does not directly regulate expression of the leu operon promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.